Sodium Valproate

Sodium salt of Valproic Acid

Parameters Results
Name Sodium Valproate
Quality BP/EP/USP
IUPAC Name Sodium 2-propyl pentanoate
Molecular Formula C8H15NaO2
Molecular Weight 166.19567 gm/mol
CAS Number 1069-66-5
Physical Appearance A White or almost white crystalline, hygroscopic powder
Solubility Very slight soluble in water, Slightly or freely soluble in alcohol
Identification by IR Absorption Complies the test as per BP/EP/USP
Identification by GC Complies the test as per BP/EP/USP
Reaction of Sodium Solution gives reaction characteristics of Sodium
Appearance of solution Test solution should be less opalescent than reference suspension II and should be less intensely colored than reference solution
Loss on Drying Not more than 2% w/w
Acidity or Alkalinity Not more than 0.75 ml of 0.1M Hydrochloric Acid or 0.1M Sodium Hydroxide is required to change the colour of the indicator
Chlorides Not more than 200 ppm
Sulphates Not more than 200 ppm
Heavy Metals Not more than 20 ppm
Related substances by GC
Any individual impurity
Total impurities

Not more than 0.1%
Not more than 0.3%
Assay (on dry basis) Between 98.5% to 101% w/w