Riboflavin 5'-Phosphate Sodium

Sodium salt of Vitamin B2

Parameters Results
Name Riboflavin 5'-Phosphate Sodium
Quality BP/EP/USP
IUPAC Name sodium [5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)-2,3,4-trihydroxypentyl] hydrogen phosphate
Molecular Formula C17H20N4O9P.Na
Molecular Weight 478.33 gm/mol
CAS Number 130-40-5
Physical Appearance A fine Orange Yellow, Hygroscopic crystalline powder
Solubility Soluble in water, Insoluble in Ethanol
Identification by UV Absorption Complies the test as per BP/EP/USP
Identification by Sodium & Phosphate Test Complies the test as per BP/EP/USP
Specific Rotation Between +37.0 and +42.0
pH 5.0 to 6.5
Loss on Drying Not more than 7.5%
Residue on Ignition Not more than 0.2% w/w
Free Phosphate Not more than 1%
Free Riboflavin Not more than 6%
Riboflavin Diphosphate Not more than 6%
Lumiflavin Not more than 0.025%
Volatile Impurities
Chloroform
1,4 Dioxane
Methyl Chloride
Trichloro Ethylene

Not more than 60 ppm
Not more than 380 ppm
Not more than 600 ppm
Not more than 80 ppm
Particle Size 95% should pass through #60 mesh sieve
Assay (on dry basis) 73% and 79% w/w as C17H20N4O6